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     aids and the black plague
       has anyone heard of this..

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kill3rqu3en

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i recently heard a theory that decendants of people who had the black plague and survivered have a natural defense system against aids. i was wondering if anyone else has heard of this?


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Posts: 5 | Posted: 01:42 AM on August 16, 2006 | IP
EntwickelnCollin

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I've never heard the claim, but I highly doubt it.

AIDS is a virus; the bubonic plague is a bacteria. Immunity to a bacteria shouldn't help against any kind of virus. The bubonic plague did infect the lymph nodes, however, which are part of the body's immune system, and AIDS attacks the immune system. There may be a connection, but I doubt it.


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Posts: 729 | Posted: 3:12 PM on August 17, 2006 | IP
derwood

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Quote from kill3rqu3en at 01:42 AM on August 16, 2006 :
i recently heard a theory that decendants of people who had the black plague and survivered have a natural defense system against aids. i was wondering if anyone else has heard of this?


Yes.

HIV and Yersinia pestis both used a chemokine receptor to gain access to human cells, HIV by actually getting into cells, and Y. pestis, if I remember correctly, to bind to human cells.  No binding, no infection (or at least not as bad of an infection).

The receptor in question is called CCR5.





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Posts: 1646 | Posted: 2:58 PM on October 5, 2010 | IP
    
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